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Mois : juillet 2022

Pr Denis David is laureate of the Schaefer award

Four scientists at Columbia University Vagelos College of Physicians and Surgeons have received awards from the Schaefer Research Scholars Program, made possible through a bequest from Dr. Ludwig Schaefer. Each award consists of a $50,000 cash prize and up to $200,000 in direct research support. Pr David is a visiting faculty who iscollaborating with VP&S faculty.…
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CYP 450 enzymes influence (R,S)-ketamine brain delivery and its antidepressant activity

This review describes (R,S)-ketamine pharmacodynamics and pharmacokinetics to alert clinicians about possible drug-drug interactions during a concomitant administration of (R,S)-ketamine and CYP inducers/inhibitors that could enhance or blunt, respectively, (R,S)-ketamine’s therapeutic antidepressant efficacy in patients. https://pubmed.ncbi.nlm.nih.gov/34965407/