Université Paris Saclay, Bâtiment Henri Moissan
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Publications

2023

Nguyen, T. M. L., F. Jollant, L. Tritschler, R. Colle, E. Corruble and A. M. Gardier (2023). « Pharmacological Mechanism of Ketamine in Suicidal Behavior Based on Animal Models of Aggressiveness and Impulsivity: A Narrative Review. » Pharmaceuticals (Basel) 16(4).

Nguyen, T. M. L., C. Defaix, I. Mendez-David, L. Tritschler, I. Etting, J. C. Alvarez, W. Choucha, R. Colle, E. Corruble, D. J. David and A. M. Gardier (2023). « Intranasal (R, S)-ketamine delivery induces sustained antidepressant effects associated with changes in cortical balance of excitatory/inhibitory synaptic activity. » Neuropharmacology 225: 109357.

Mendez-David, I., D. J. David, C. Delomenie, L. Tritchler, J. M. Beaulieu, R. Colle, E. Corruble, A. M. Gardier and R. Hen (2023). « A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin. » Hippocampus.

Jollant, F., R. Colle, T. M. L. Nguyen, E. Corruble, A. M. Gardier, M. Walter, M. Abbar and G. Wagner (2023). « Ketamine and esketamine in suicidal thoughts and behaviors: a systematic review. » Ther Adv Psychopharmacol 13: 20451253231151327.

Doan, J., C. Defaix, I. Mendez-David, A. M. Gardier, R. Colle, E. Corruble, J. C. McGowan, D. J. David, J. P. Guilloux and L. Tritschler (2023). « Intrahippocampal injection of a selective blocker of NMDA receptors containing the GluN2B subunit, Ro25-6981, increases glutamate neurotransmission and induces antidepressant-like effects. » Fundam Clin Pharmacol.

2022

Ait Tayeb, A. E. K., R. Colle, K. Chappell, K. El-Asmar, C. Acquaviva-Bourdain, D. J. David, S. Trabado, P. Chanson, B. Feve, L. Becquemont, C. Verstuyft and E. Corruble (2023). « Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment. » Psychol Med: 1-10.

Mesdom, P., R. Colle, L. Becquemont, K. Chappell, D. J. David, I. Mendez-David, E. Corruble and C. Verstuyft (2022). « Tobacco use is associated with low peripheral beta-arrestin 1 levels in major depression: A preliminary report. » Drug Alcohol Depend 240: 109653.

Lebeau, R. H., I. Mendez-David, L. Kucynski-Noyau, C. Henry, D. Attali, M. Plaze, R. Colle, E. Corruble, A. M. Gardier, R. Gaillard, J. P. Guilloux and D. J. David (2022). « Peripheral proteomic changes after electroconvulsive seizures in a rodent model of non-response to chronic fluoxetine. » Front Pharmacol 13: 993449.

Poinsignon, V., R. Colle, K. E. Asmar, I. Mendez-David, D. J. David, A. E. K. Ait Tayeb, K. Chappell, F. Gressier, H. Herrero, B. Feve, L. Becquemont, E. Corruble and C. Verstuyft (2022). « The GG genotype of the serotonin 4 receptor genetic polymorphism, rs1345697, is associated with lower remission rates after antidepressant treatment: Findings from the METADAP cohort. » J Affect Disord 299: 335-343.

Nguyen, T. M. L., J. C. McGowan and A. M. Gardier (2022). « CYP 450 enzymes influence (R,S)-ketamine brain delivery and its antidepressant activity. » Neuropharmacology 206: 108936.

Mendez-David, I., R. Schofield, L. Tritschler, R. Colle, J. P. Guilloux, A. M. Gardier, E. Corruble, R. Hen and D. J. David (2022). « Reviving through human hippocampal newborn neurons. » Encephale 48(2): 179-187.

2021

Reach, P., I. Lazareth, F. Coudore, A. Stansal, R. Attal, U. Michon-Pasturel, P. Ghaffari, A. Yannoutsos, H. Beaussier, E. Sacco, M. Wang, P. Priollet, J. P. Lefaucheur and M. Zuber (2021). « A reappraisal of the presence of small or large fiber neuropathy in patients with erythromelalgia. » Neurophysiol Clin 51(4): 349-355.

Mongongu, C., F. Coudore, V. Domergue, M. Ericsson, C. Buisson and A. Marchand (2021). « Detection of LongR(3) -IGF-I, Des(1-3)-IGF-I, and R(3) -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes. » Drug Test Anal 13(7): 1256-1269.

Dallerac, G., X. Li, P. Lecouflet, N. Morisot, S. Sacchi, R. Asselot, T. H. Pham, B. Potier, D. J. G. Watson, S. Schmidt, G. Levasseur, P. Fossat, A. Besedin, J. M. Rivet, J. T. Coyle, G. Collo, L. Pollegioni, J. Kehr, M. Galante, K. C. Fone, A. M. Gardier, T. Freret, A. Contarino, M. J. Millan and J. P. Mothet (2021). « Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor coagonist d-serine. » Proc Natl Acad Sci U S A 118(23).

Balayssac, D., B. Pereira, P. Cuq, J. Douris, L. Ferrari, E. Boutet-Robinet, M. Lechevrel, C. Demeilliers, P. Rat, F. Coudore, E. Verron, B. Lacarelle, J. Guitton, A. Courtois, D. Allorge, S. Pain, M. Guerbet, A. Collin, B. Vennat, G. Brousse, N. Authier and C. Laporte (2021). « Perception of pharmacy students toward opioid-related disorders and roles of community pharmacists: A French nationwide cross-sectional study. » Subst Abus 42(4): 706-715.

Ait Tayeb, A. E. K., R. Colle, K. El-Asmar, K. Chappell, C. Acquaviva-Bourdain, D. J. David, S. Trabado, P. Chanson, B. Feve, L. Becquemont, C. Verstuyft and E. Corruble (2021). « Plasma acetyl-l-carnitine and l-carnitine in major depressive episodes: a case-control study before and after treatment. » Psychol Med: 1-10.

2020

Petitjean, G., F. Aman-Pommier, F. Coudore, N. El Helali and A. Le Monnier (2020). « A rapid, automatic and accurate assay for quantifying temocillin in human serum and CSF using turbulent flow liquid chromatography coupled to high-resolution mass spectrometry. Clinical application. » Biomed Chromatogr 34(2): e4759.

Mongongu, C., E. M. Moussa, F. Semence, I. Roulland, M. Ericsson, F. Coudore, A. Marchand and C. Buisson (2020). « Use of capillary dried blood for quantification of intact IGF-I by LC-HRMS for antidoping analysis. » Bioanalysis 12(11): 737-752.

Colle, R., K. El Asmar, C. Verstuyft, P. M. Lledo, F. Lazarini, K. Chappell, E. Deflesselle, A. E. K. Ait Tayeb, B. Falissard, E. Duron, S. Rotenberg, J. F. Costemale-Lacoste, D. J. David, F. Gressier, A. M. Gardier, T. Hummel, L. Becquemont and E. Corruble (2020). « The olfactory deficits of depressed patients are restored after remission with venlafaxine treatment. » Psychol Med: 1-9.

Pham, T. H., C. Defaix, T. M. L. Nguyen, I. Mendez-David, L. Tritschler, D. J. David and A. M. Gardier (2020). « Cortical and raphe GABAA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine. » Pharmacol Biochem Behav 192: 172913.

Petitjean, G., F. Aman-Pommier, F. Coudore, N. El Helali and A. Le Monnier (2020). « A rapid, automatic and accurate assay for quantifying temocillin in human serum and CSF using turbulent flow liquid chromatography coupled to high-resolution mass spectrometry. Clinical application. » Biomed Chromatogr 34(2): e4759.

Mongongu, C., E. M. Moussa, F. Semence, I. Roulland, M. Ericsson, F. Coudore, A. Marchand and C. Buisson (2020). « Use of capillary dried blood for quantification of intact IGF-I by LC-HRMS for antidoping analysis. » Bioanalysis 12(11): 737-752.

Faye, C., R. Hen, B. P. Guiard, C. A. Denny, A. M. Gardier, I. Mendez-David and D. J. David (2020). « Rapid Anxiolytic Effects of RS67333, a Serotonin Type 4 Receptor Agonist, and Diazepam, a Benzodiazepine, Are Mediated by Projections From the Prefrontal Cortex to the Dorsal Raphe Nucleus. » Biol Psychiatry 87(6): 514-525.

Colle, R., P. Masson, C. Verstuyft, B. Feve, E. Werner, C. Boursier-Neyret, B. Walther, D. J. David, B. Boniface, B. Falissard, P. Chanson,E. Corruble and L. Becquemont (2020). « Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study. » Psychiatry Clin Neurosci 74(2): 112-117.

Chen, B. K., I. Mendez-David, V. M. Luna, C. Faye, A. M. Gardier, D. J. David and C. A. Denny (2020). « Prophylactic efficacy of 5-HT4R agonists against stress. » Neuropsychopharmacology 45(3): 542-552.

Chen, B. K., V. M. Luna, C. T. LaGamma, X. Xu, S. X. Deng, R. F. Suckow, T. B. Cooper, A. Shah, R. A. Brachman, I. Mendez-David, D. J. David, A. M. Gardier, D. W. Landry and C. A. Denny (2020). « Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine. » Neuropsychopharmacology 45(9): 1545-1556.

Agasse, F., I. Mendez-David, W. Christaller, R. Carpentier, B. Y. Braz, D. J. David, F. Saudou and S. Humbert (2020). « Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. » Cell Rep 32(1): 107865.

2019

Tutakhail, A., Q. A. Nazari, S. Khabil, A. Gardier and F. Coudore (2019). « Muscular and mitochondrial effects of long-term fluoxetine treatment in mice, combined with physical endurance exercise on treadmill. » Life Sci 232: 116508.

Pham, T. H. and A. M. Gardier (2019). « Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies. » Pharmacol Ther 199: 58-90.

Feng, J., S. Lepetre-Mouelhi, A. Gautier, S. Mura, C. Cailleau, F. Coudore, M. Hamon and P. Couvreur (2019). « A new painkiller nanomedicine to bypass the blood-brain barrier and the use of morphine. » Sci Adv 5(2): eaau5148.

Doan, J., A. M. Gardier and L. Tritschler (2019). « Role of adult-born granule cells in the hippocampal functions: Focus on the GluN2B-containing NMDA receptors. » Eur Neuropsychopharmacol 29(10): 1065-1082.

Colle, R., A. E. K. Ait Tayeb, P. Mesdom, M. de Menthon, L. Becquemont, C. Verstuyft, D. J. David, O. Lambotte and E. Corruble (2019). « Methemoglobinemia as a biomarker of dapsone-induced mania severity. » J Affect Disord 254: 122-123.

Zhang, H., C. Zhang, J. Vincent, D. Zala, C. Benstaali, M. Sainlos, D. Grillo-Bosch, S. Daburon, F. Coussen, Y. Cho, D. J. David, F. Saudou, Y. Humeau and D. Choquet (2018). « Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models. » Nat Commun 9(1): 4272.

2018

Tutakhail, A., Q. A. Nazary, D. Lebsir, S. Kerdine-Romer and F. Coudore (2018). « Induction of brain Nrf2-HO-1 pathway and antinociception after different physical training paradigms in mice. » Life Sci209: 149-156.

Tritschler, L., M. A. Kheirbek, Y. L. Dantec, I. Mendez-David, J. P. Guilloux, C. Faye, J. Doan, T. H. Pham, R. Hen, D. J. David and A. M. Gardier (2018). « Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. » Neurosci Res 134: 56-60.

Tritschler, L., R. Gaillard, A. M. Gardier, D. J. David and J. P. Guilloux (2018). « [Consequences of the monoaminergic systems cross-talk in the antidepressant activity]. » Encephale 44(3): 264-273.

Pham, T. H., C. Defaix, X. Xu, S. X. Deng, N. Fabresse, J. C. Alvarez, D. W. Landry, R. A. Brachman, C. A. Denny and A. M. Gardier (2018). « Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects. » Biol Psychiatry 84(1): e3-e6.

Petit, A. C., K. El Asmar, D. J. David, A. M. Gardier, L. Becquemont, B. Feve, C. Verstuyft and E. Corruble (2018). « The association of beta-arrestin2 polymorphisms with response to antidepressant treatment in depressed patients. » Prog Neuropsychopharmacol Biol Psychiatry 81: 74-79.

Felice, D., J. P. Guilloux, A. Pehrson, Y. Li, I. Mendez-David, A. M. Gardier, C. Sanchez and D. J. David (2018). « Vortioxetine Improves Context Discrimination in Mice Through a Neurogenesis Independent Mechanism. » Front Pharmacol 9: 204.

Delmotte, J. B., A. Tutakhail, K. Abdallah, P. Reach, M. D’Ussel, G. Deplanque, H. Beaussier and F. Coudore (2018). « Electrochemical Skin Conductance as a Marker of Painful Oxaliplatin-Induced Peripheral Neuropathy. » Neurol Res Int 2018: 1254602.

Delmotte, J. B., H. Beaussier, N. Auzeil, F. Massicot, O. Laprevote, E. Raymond and F. Coudore (2018). « Is quantitative sensory testing helpful in the management of oxaliplatin neuropathy? a two-year clinical study. » Cancer Treat Res Commun 17: 31-36.

Deflesselle, E., R. Colle, L. Rigal, D. J. David, A. Vievard, S. Martin, L. Becquemont, C. Verstuyft and E. Corruble (2018). « The TRKB rs2289656 genetic polymorphism is associated with acute suicide attempts in depressed patients: A transversal case control study. » PLoS One 13(10): e0205648.

Defaix, C., A. Solgadi, T. H. Pham, A. M. Gardier, P. Chaminade and L. Tritschler (2018). « Rapid analysis of glutamate, glutamine and GABA in mice frontal cortex microdialysis samples using HPLC coupled to electrospray tandem mass spectrometry. » J Pharm Biomed Anal 152: 31-38.

Colle, R., F. Boichot, E. Bouteiller, C. Elie-Lefebvre, P. Hardy, D. J. David, C. Verstuyft and E. Corruble (2018). « Restless Legs Syndrome and Schizophrenia: A Case Report. » J Clin Psychopharmacol 38(1): 91-92.

Colle, R., A. E. K. Ait Tayeb, P. Mesdom, M. de Menthon, L. Becquemont, C. Verstuyft, D. J. David, O. Lambotte and E. Corruble (2018). « Methemoglobinemia as a biomarker of dapsone-induced mania severity. » J Affect Disord.

2017

Pham, T. H., I. Mendez-David, C. Defaix, B. P. Guiard, L. Tritschler, D. J. David and A. M. Gardier (2017). « Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice. » Neuropharmacology 112(Pt A): 198-209.

Mendez-David, I., J. P. Guilloux, M. Papp, L. Tritschler, E. Mocaer, A. M. Gardier, S. Bretin and D. J. David (2017). « S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. » Front Pharmacol 8: 462.

Mendez-David, I., C. Boursier, V. Domergue, R. Colle, B. Falissard, E. Corruble, A. M. Gardier, J. P. Guilloux and D. J. David (2017). « Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression. » Front Cell Neurosci 11: 237.

Mekiri, M., A. M. Gardier, D. J. David and J. P. Guilloux (2017). « Chronic corticosterone administration effects on behavioral emotionality in female c57bl6 mice. » Exp Clin Psychopharmacol 25(2): 94-104.

Lugert, S., T. Kremer, R. Jagasia, A. Herrmann, S. Aigner, C. Giachino, I. Mendez-David, A. M. Gardier, J. P. Carralot, H. Meistermann, A. Augustin, M. D. Saxe, J. Lamerz, G. Duran-Pacheco, A. Ducret, V. Taylor, D. J. David and C. Czech (2017). « Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. » Sci Rep 7: 46543.

Guilloux, J. P., B. A. Samuels, I. Mendez-David, A. Hu, M. Levinstein, C. Faye, M. Mekiri, E. Mocaer, A. M. Gardier, R. Hen, A. Sors and D. J. David (2017). « S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. » Sci Rep 7: 42946.

Guilloux, J. P., A. M. Gardier and D. J. David (2017). « New targets and modalities of antidepressant drugs development. » La lettre du Pharmacologue 31(1): 12-18.

Garcia-Garcia, A. L., Q. Meng, S. Canetta, A. M. Gardier, B. P. Guiard, C. Kellendonk, A. Dranovsky and E. D. Leonardo (2017). « Serotonin Signaling through Prefrontal Cortex 5-HT1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors. » Cell Rep 18(5): 1144-1156.

Felice, D., A. M. Gardier, C. S. Sanchez and D. J. David (2017). Innovative Solutions to the Development of Novel Antidepressants. Frontiers in Drug Discovery, Bentham Science Publishers. 2: 3-43.

Faye, C., J. C. McGowan, C. A. Denny and D. J. David (2017). « Neurobiological mechanisms of stress resilience and implications for the aged population. » Curr Neuropharmacol.

Deflesselle, E., C. Verstuyft, A. C. Petit, P. Hardy, D. J. David, B. Falissard, B. Feve, L. Rigal, L. Becquemont, E. Corruble and R. Colle (2017). « No impact of eight NTRK2 genetic polymorphisms on 6-month antidepressant efficacy in depressed patients. » Pharmacogenomics 18(4): 349-357.

Colle, R., S. Trabado, D. J. David, S. Brailly-Tabard, P. Hardy, B. Falissard, B. Feve, L. Becquemont, C. Verstuyft and E. Corruble (2017). « Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients. » Neuropsychobiology 75(1): 39-45.

Andriamamonjy, M., J. B. Delmotte, F. Savinelli, H. Beaussier and F. Coudore (2017). « Quantification of Chronic Oxaliplatin-Induced Hypesthesia in Two Areas of the Hand. » J Clin Neurophysiol 34(2): 126-131.

2016

Siopi, E., M. Denizet, M. M. Gabellec, F. de Chaumont, J. C. Olivo-Marin, J. P. Guilloux, P. M. Lledo and F. Lazarini (2016). « Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice. » J Neurosci 36(2): 518-531.

Samuels, B. A., I. Mendez-David, C. Faye, S. A. David, K. A. Pierz, A. M. Gardier, R. Hen and D. J. David (2016). « Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants. » Neuroscientist 22(1): 26-45.

Qesseveur, G., A. C. Petit, H. T. Nguyen, L. Dahan, R. Colle, S. Rotenberg, I. Seif, P. Robert, D. David, J. P. Guilloux, A. M. Gardier, C. Verstuyft, L. Becquemont, E. Corruble and B. P. Guiard (2016). « Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. » Neuropharmacology 105: 142-153.

Nautiyal, K. M., L. Tritschler, S. E. Ahmari, D. J. David, A. M. Gardier and R. Hen (2016). « A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors. » Neuropsychopharmacology 41(12): 2941-2950.

David, D. J., L. Tritschler, J. P. Guilloux, A. M. Gardier, C. Sanchez and R. Gaillard (2016). « [Pharmacological properties of vortioxetine and its pre-clinical consequences]. » Encephale 42(1 Suppl 1): 1S12-23.

David, D. J. and D. Gourion (2016). « [Antidepressant and tolerance: Determinants and management of major side effects]. » Encephale 42(6): 553-561.

David, D. J. and A. M. Gardier (2016). « [The pharmacological basis of the serotonin system: Application to antidepressant response]. » Encephale 42(3): 255-263.

Darcet, F., A. M. Gardier, R. Gaillard, D. J. David and J. P. Guilloux (2016). « Cognitive Dysfunction in Major Depressive Disorder. A Translational Review in Animal Models of the Disease. » Pharmaceuticals (Basel) 9(1).

Darcet, F., A. M. Gardier, D. J. David and J. P. Guilloux (2016). « Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression. » Neurosci Lett 616: 197-203.

Costemale-Lacoste, J. F., J. P. Guilloux and R. Gaillard (2016). « The role of GSK-3 in treatment-resistant depression and links with the pharmacological effects of lithium and ketamine: A review of the literature. » Encephale 42(2): 156-164.

Corvol, J. C., S. Goni, R. Bordet and R. T. N. participants of the Giens Xxxi (2016). « Translational research on cognitive and behavioural disorders in neurological and psychiatric diseases. » Therapie 71(1): 1-13, 15-26.

Brachman, R. A., J. C. McGowan, J. N. Perusini, S. C. Lim, T. H. Pham, C. Faye, A. M. Gardier, I. Mendez-David, D. J. David, R. Hen and C. A. Denny (2016). « Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior. » Biol Psychiatry 79(9): 776-786.

Besson, M., S. Guiducci, S. Granon, J. P. Guilloux, B. Guiard, C. Reperant, P. Faure, S. Pons, G. Cannazza, M. Zoli, A. M. Gardier and U. Maskos (2016). « Alterations in alpha5* nicotinic acetylcholine receptors result in midbrain- and hippocampus-dependent behavioural and neural impairments. » Psychopharmacology (Berl) 233(18): 3297-3314.

2015

Schloesser, R. J., S. Orvoen, D. V. Jimenez, N. F. Hardy, K. R. Maynard, M. Sukumar, H. K. Manji, A. M. Gardier, D. J. David and K. Martinowich (2015). « Antidepressant-like Effects of Electroconvulsive Seizures Require Adult Neurogenesis in a Neuroendocrine Model of Depression. » Brain Stimul 8(5): 862-867.

Nautiyal, K. M., K. F. Tanaka, M. M. Barr, L. Tritschler, Y. Le Dantec, D. J. David, A. M. Gardier, C. Blanco, R. Hen and S. E. Ahmari (2015). « Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity. » Neuron 86(3): 813-826.

Mendez-David, I., L. Tritschler, Z. E. Ali, M. H. Damiens, M. Pallardy, D. J. David, S. Kerdine-Romer and A. M. Gardier (2015). « Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression. » Neurosci Lett 597: 121-126.

Mendez-David, I., D. J. David, J.-P. Guilloux, R. Hen and A. M. Gardier (2015). 5-HT4 Receptor Subtype, β-Arrestin Level, and Rapid-Onset Effects of Antidepressant Drugs. 95: 101-121.

Hache, G., B. P. Guiard, T. H. Nguyen, G. Quesseveur, A. M. Gardier, D. Peters, G. Munro and F. Coudore (2015). « Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain. » Eur J Pain 19(3): 322-333.

Felice, D., O. F. O’Leary, J. F. Cryan, T. G. Dinan, A. M. Gardier, C. Sanchez and D. J. David (2015). « When ageing meets the blues: Are current antidepressants effective in depressed aged patients? » Neurosci Biobehav Rev 55: 478-497.

Ding, Y., L. C. Chang, X. Wang, J. P. Guilloux, J. Parrish, H. Oh, B. J. French, D. A. Lewis, G. C. Tseng and E. Sibille (2015). « Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging. » Mol Neuropsychiatry 1(1): 1-12.

Courousse, T., A. Bacq, C. Belzung, B. Guiard, L. Balasse, F. Louis, A. M. Le Guisquet, A. M. Gardier, A. H. Schinkel, B. Giros and S. Gautron (2015). « Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3beta signaling. » Mol Psychiatry 20(7): 889-900.

Colle, R., F. Gressier, C. Verstuyft, E. Deflesselle, J. P. Lepine, F. Ferreri, P. Hardy, J. P. Guilloux, A. C. Petit, B. Feve, B. Falissard, L. Becquemont and E. Corruble (2015). « Brain-derived neurotrophic factor Val66Met polymorphism and 6-month antidepressant remission in depressed Caucasian patients. » J Affect Disord 175: 233-240.

Colle, R., E. Deflesselle, S. Martin, D. J. David, P. Hardy, A. Taranu, B. Falissard, C. Verstuyft and E. Corruble (2015). « BDNF/TRKB/P75NTR polymorphisms and their consequences on antidepressant efficacy in depressed patients. » Pharmacogenomics 16(9): 997-1013.

2014

Tritschler, L., D. Felice, R. Colle, J. P. Guilloux, E. Corruble, A. M. Gardier and D. J. David (2014). « Vortioxetine for the treatment of major depressive disorder. » Expert Rev Clin Pharmacol 7(6): 731-745.

Samuels, B., I. David, D. J. David, A. M. Gardier and R. Hen (2014). Role of hippocampal neurogenesis in the mechanism of action of antidepressant/anxiolytic drugs in animal model of depression and anxiety. Neurobiology of mood disorders. B. P. Guiard and E. Dremencov, Bentham Science Publishers210-233.

Quesseveur, G. and B. P. Guiard (2014). New Strategies for the Treatment of Mood Disorders: The Triple Reuptake Inhibitors. Neurobiology of mood disorders. B. P. Guiard and E. Dremencov, Bentham Science Publishers234-253.

Pla, P., S. Orvoen, F. Saudou, D. J. David and S. Humbert (2014). « Mood disorders in Huntington’s disease: from behavior to cellular and molecular mechanisms. » Front Behav Neurosci 8: 135.

Petit, A. C., G. Quesseveur, F. Gressier, R. Colle, D. J. David, A. M. Gardier, F. Ferreri, J. P. Lepine, B. Falissard, C. Verstuyft, B. P. Guiard and E. Corruble (2014). « Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder. » Prog Neuropsychopharmacol Biol Psychiatry 54: 76-82.

Mendez-David, I., D. J. David, F. Darcet, M. V. Wu, S. Kerdine-Romer, A. M. Gardier and R. Hen (2014). « Rapid anxiolytic effects of a 5-HT(4) receptor agonist are mediated by a neurogenesis-independent mechanism. » Neuropsychopharmacology 39(6): 1366-1378.

Le Dantec, Y., G. Hache, J. P. Guilloux, B. P. Guiard, D. J. David, J. Adrien and P. Escourrou (2014). « NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration. » Neuroscience 274: 357-368.

Gaudin, A., M. Yemisci, H. Eroglu, S. Lepetre-Mouelhi, O. F. Turkoglu, B. Donmez-Demir, S. Caban, M. F. Sargon, S. Garcia-Argote, G. Pieters, O. Loreau, B. Rousseau, O. Tagit, N. Hildebrandt, Y. Le Dantec, J. Mougin, S. Valetti, H. Chacun, V. Nicolas, D. Desmaele, K. Andrieux, Y. Capan, T. Dalkara and P. Couvreur (2014). « Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury. » Nat Nanotechnol 9(12): 1054-1062.

Gardier, A. M. (2014). Intracerebral in vivo microdialysis in knockout mice : advantages and drawbacks. Neurobiology of mood disorders. B. P. Guiard and E. Dremencov, Bentham Science Publishers3-22.

Darcet, F., I. Mendez-David, L. Tritschler, A. M. Gardier, J. P. Guilloux and D. J. David (2014). « Learning and memory impairments in a neuroendocrine mouse model of anxiety/depression. » Front Behav Neurosci 8: 136.

Ansar, S., E. Chatzikonstantinou, R. Thiagarajah, L. Tritschler, M. Fatar, M. G. Hennerici and S. Meairs (2014). « Pro-inflammatory mediators and apoptosis correlate to rt-PA response in a novel mouse model of thromboembolic stroke. » PLoS One 9(1): e85849.

2013

Tolu, S., R. Eddine, F. Marti, V. David, M. Graupner, S. Pons, M. Baudonnat, M. Husson, M. Besson, C. Reperant, J. Zemdegs, C. Pages, Y. A. Hay, B. Lambolez, J. Caboche, B. Gutkin, A. M. Gardier, J. P. Changeux, P. Faure and U. Maskos (2013). « Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement. » Mol Psychiatry 18(3): 382-393.

Quesseveur, G., C. Reperant, D. J. David, A. M. Gardier, C. Sanchez and B. P. Guiard (2013). « 5-HT(2)A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system. » Exp Brain Res 226(2): 285-295.

Quesseveur, G., A. M. Gardier and B. P. Guiard (2013). « The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs. » Curr Drug Targets 14(11): 1277-1294.

Quesseveur, G., D. J. David, M. C. Gaillard, P. Pla, M. V. Wu, H. T. Nguyen, V. Nicolas, G. Auregan, I. David, A. Dranovsky, P. Hantraye, R. Hen, A. M. Gardier, N. Deglon and B. P. Guiard (2013). « BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. » Transl Psychiatry 3: e253.

Pla, P., S. Orvoen, C. Benstaali, S. Dodier, A. M. Gardier, D. J. David, S. Humbert and F. Saudou (2013). « Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse. » PLoS One 8(9): e73902.

Nguyen, H. T., B. P. Guiard, A. Bacq, D. J. David, I. David, G. Quesseveur, S. Gautron, C. Sanchez and A. M. Gardier (2013). « Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: an in vivo microdialysis study in mice. » Br J Pharmacol 168(1): 103-116.

Mendez-David, I., R. Hen, A. M. Gardier and D. J. David (2013). « Adult hippocampal neurogenesis: an actor in the antidepressant-like action. » Ann Pharm Fr 71(3): 143-149.

Mendez-David, I., Z. El-Ali, R. Hen, B. Falissard, E. Corruble, A. M. Gardier, S. Kerdine-Romer and D. J. David (2013). « A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: beta-arrestin 1 protein levels in depression and treatment. » Front Pharmacol 4: 124.

Massicot, F., G. Hache, L. David, D. Chen, C. Leuxe, L. Garnier-Legrand, P. Rat, O. Laprevote and F. Coudore (2013). « P2X7 Cell Death Receptor Activation and Mitochondrial Impairment in Oxaliplatin-Induced Apoptosis and Neuronal Injury: Cellular Mechanisms and In Vivo Approach. » PLoS One 8(6): e66830.

Guilloux, J. P., I. Mendez-David, A. Pehrson, B. P. Guiard, C. Reperant, S. Orvoen, A. M. Gardier, R. Hen, B. Ebert, S. Miller, C. Sanchez and D. J. David (2013). « Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. » Neuropharmacology 73: 147-159.

Guiard, B. (2013). « Glia: a new cellular target in the treatment of major depression. » Curr Drug Targets 14(11): 1219.

 Gardier, A. M. (2013). « Antidepressant activity: contribution of brain microdialysis in knock-out mice to the understanding of BDNF/5-HT transporter/5-HT autoreceptor interactions. » Front Pharmacol 4: 98.

Douillard-Guilloux, G., J. P. Guilloux, D. A. Lewis and E. Sibille (2013). « Anticipated brain molecular aging in major depression. » Am J Geriatr Psychiatry 21(5): 450-460.

David, D. J., B. P. Guiard, J. P. Guilloux and A. M. Gardier (2013). Pharmacologie des antidépresseurs : modèles animaux. Les Antidépresseurs. E. Corruble. Paris, Flammarion Médecine/Sciences40-51.

Ben M’Barek, K., P. Pla, S. Orvoen, C. Benstaali, J. D. Godin, A. M. Gardier, F. Saudou, D. J. David and S. Humbert (2013). « Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. » J Neurosci 33(20): 8608-8620.

2012

Xia, L., C. Delomenie, I. David, Q. Rainer, M. Marouard, H. Delacroix, D. J. David, A. M. Gardier and J. P. Guilloux (2012). « Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT(1)A and 5-HT(1)B receptors disruption in mice. » Neurosci Lett 521(1): 20-25.

Tripp, A., H. Oh, J. P. Guilloux, K. Martinowich, D. A. Lewis and E. Sibille (2012). « Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. » Am J Psychiatry 169(11): 1194-1202.

Rainer, Q., L. Xia, J. P. Guilloux, C. Gabriel, E. Mocaer, R. Hen, E. Enhamre, A. M. Gardier and D. J. David (2012). « Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety. » Int J Neuropsychopharmacol 15(3): 321-335.

Rainer, Q., H. T. Nguyen, G. Quesseveur, A. M. Gardier, D. J. David and B. P. Guiard (2012). « Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration. » Mol Pharmacol 81(2): 106-112.

Quesseveur, G., H. T. Nguyen, A. M. Gardier and B. P. Guiard (2012). « 5-HT2 ligands in the treatment of anxiety and depression. » Expert Opin Investig Drugs 21(11): 1701-1725.

Orvoen, S., P. Pla, A. M. Gardier, F. Saudou and D. J. David (2012). « Huntington’s disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation. » Neurosci Lett 507(2): 127-132.

Hache, G., B. P. Guiard, Y. Le Dantec, S. Orvoen, D. J. David, A. M. Gardier and F. Coudore (2012). « Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. » Neuroreport 23(9): 525-529.

 Guilloux, J. P., G. Douillard-Guilloux, R. Kota, X. Wang, A. M. Gardier, K. Martinowich, G. C. Tseng, D. A. Lewis and E. Sibille (2012). « Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression. » Mol Psychiatry 17(11): 1130-1142.

Guilloux, J. P., D. J. David, B. A. Samuels, I. David, A. M. Gardier and B. P. Guiard (2012). Non-response to initial antidepressant therapy. Psychology. Rijeka, Croatia, InTech.

Deltheil, T., B. Guiard, J. P. Guilloux, D. David, F. Coudore and A. M. Gardier (2012). Sérotonine et facteurs neurotrophiques dans la dépression. Sérotonine: aspects biologiques et cliniques. O. Spreux-Varoquaux. Paris, Lavoisier – Médecine Sciences. 1: 329-370.

David, D. J. (2012). « [Mechanisms of action of antidepressive drugs: new approaches]. » Encephale 38 Suppl 2: S45-48.

Coudore, F., D. Roche, S. Lefeuvre, D. Faussot, E. M. Billaud, M. A. Loriot and P. Beaune (2012). « Validation of an ultra-high performance liquid chromatography tandem mass spectrometric method for quantifying uracil and 5,6-dihydrouracil in human plasma. » J Chromatogr Sci 50(10): 877-884.

Besson, M., V. David, M. Baudonnat, P. Cazala, J. P. Guilloux, C. Reperant, I. Cloez-Tayarani, J. P. Changeux, A. M. Gardier and S. Granon (2012). « Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. » Psychopharmacology (Berl) 220(1): 1-14.

Bacq, A., L. Balasse, G. Biala, B. Guiard, A. M. Gardier, A. Schinkel, F. Louis, V. Vialou, M. P. Martres, C. Chevarin, M. Hamon, B. Giros and S. Gautron (2012). « Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. » Mol Psychiatry 17(9): 926-939.

2011

Surget, A., A. Tanti, E. D. Leonardo, A. Laugeray, Q. Rainer, C. Touma, R. Palme, G. Griebel, Y. Ibarguen-Vargas, R. Hen and C. Belzung (2011). « Antidepressants recruit new neurons to improve stress response regulation. » Mol Psychiatry 16(12): 1177-1188.

Samuels, B. A., E. D. Leonardo, R. Gadient, A. Williams, J. Zhou, D. J. David, A. M. Gardier, E. H. Wong and R. Hen (2011). « Modeling treatment-resistant depression. » Neuropharmacology 61(3): 408-413.

Richardson-Jones, J. W., C. P. Craige, T. H. Nguyen, H. F. Kung, A. M. Gardier, A. Dranovsky, D. J. David, B. P. Guiard, S. G. Beck, R. Hen and E. D. Leonardo (2011). « Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. » J Neurosci 31(16): 6008-6018.

Liotier, J. and F. Coudore (2011). « Drug monitoring of a case of citalopram overdosage. » Drug Chem Toxicol 34(4): 420-423.

Hache, G., F. Coudore, A. M. Gardier and B. P. Guiard (2011). « Monoaminergic Antidepressants in the Relief of Pain: Potential Therapeutic Utility of Triple Reuptake Inhibitors (TRIs). » Pharmaceuticals 4(12): 285-342.

Guilloux, J. P., M. Seney, N. Edgar and E. Sibille (2011). « Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex. » J Neurosci Methods 197(1): 21-31.

Guilloux, J. P., D. J. David, L. Xia, H. T. Nguyen, Q. Rainer, B. P. Guiard, C. Reperant, T. Deltheil, M. Toth, R. Hen and A. M. Gardier (2011). « Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. » Neuropharmacology 61(3): 478-488.

Guiard, B. (2011). A New Class of Antidepressant Drugs in the Treatment of Psychiatric Disorders: The Triple Reuptake Inhibitors. Psychiatric Disorders – Trends and development. T. Uehara. Rijeka, Croatia, InTech291-316.

2010

Richardson-Jones, J. W., C. P. Craige, B. P. Guiard, A. Stephen, K. L. Metzger, H. F. Kung, A. M. Gardier, A. Dranovsky, D. J. David, S. G. Beck, R. Hen and E. D. Leonardo (2010). « 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. » Neuron 65(1): 40-52.

Reperant, C., S. Pons, E. Dufour, H. Rollema, A. M. Gardier and U. Maskos (2010). « Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area. » Neuropharmacology 58(2): 346-350.

Popa, D., J. Cerdan, C. Reperant, B. P. Guiard, J. P. Guilloux, D. J. David and A. M. Gardier (2010). « A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. » Eur J Pharmacol 628(1-3): 83-90.

Guilloux, J. P., C. Gaiteri and E. Sibille (2010). « Network analysis of positional candidate genes of schizophrenia highlights…more than… myelin-related pathways. » Mol Psychiatry 15(8): 786-788.

Gaiteri, C., J. P. Guilloux, D. A. Lewis and E. Sibille (2010). « Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression. » PLoS One 5(4): e9970.

David, D. J., J. Wang, B. A. Samuels, Q. Rainer, I. David, A. M. Gardier and R. Hen (2010). « Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. » Neuroscientist 16(5): 578-591.

Cazorla, M., A. Jouvenceau, C. Rose, J. P. Guilloux, C. Pilon, A. Dranovsky and J. Premont (2010). « Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice. » PLoS One 5(3): e9777.

Amilhon, B., E. Lepicard, T. Renoir, R. Mongeau, D. Popa, O. Poirel, S. Miot, C. Gras, A. M. Gardier, J. Gallego, M. Hamon, L. Lanfumey, B. Gasnier, B. Giros and S. El Mestikawy (2010). « VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. » J Neurosci 30(6): 2198-2210.

2009

Real, C., I. Seif, J. Adrien and P. Escourrou (2009). « Ondansetron and fluoxetine reduce sleep apnea in mice lacking monoamine oxidase A. » Respir Physiol Neurobiol 168(3): 230-238.

Rainer, Q., A. M. Gardier, R. Hen and D. J. David (2009). « [Neurogenesis-dependent and independent effects of anti-depressant drugs]. » Med Sci (Paris) 25(10): 795-798.

Ibarguen-Vargas, Y., A. Surget, P. Vourc’h, S. Leman, C. R. Andres, A. M. Gardier and C. Belzung (2009). « Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress. » Behav Brain Res 202(2): 245-251.

Guiard, B. P., M. El Mansari and P. Blier (2009). « Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors. » Curr Drug Targets 10(11): 1069-1084.

Gardier, A. M., B. P. Guiard, J. P. Guilloux, C. Reperant, F. Coudore and D. J. David (2009). « Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review. » Fundam Clin Pharmacol 23(1): 23-42.

Gardier, A. M. (2009). « Mutant mouse models and antidepressant drug research: focus on serotonin and brain-derived neurotrophic factor. » Behav Pharmacol 20(1): 18-32.

Deltheil, T., K. Tanaka, C. Reperant, R. Hen, D. J. David and A. M. Gardier (2009). « Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice. » Int J Neuropsychopharmacol 12(7): 905-915.

David, D. J., B. A. Samuels, Q. Rainer, J. W. Wang, D. Marsteller, I. Mendez, M. Drew, D. A. Craig, B. P. Guiard, J. P. Guilloux, R. P. Artymyshyn, A. M. Gardier, C. Gerald, I. A. Antonijevic, E. D. Leonardo and R. Hen (2009). « Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. » Neuron 62(4): 479-493.

David, D. J., A. M. Gardier, J. Wang, B. Samuels and R. Hen (2009). Assay For Screening Antidepressant. Neuron. C. University and U. P. Sud. USA. 36682.

Authier, N., D. Balayssac, F. Marchand, B. Ling, A. Zangarelli, J. Descoeur, F. Coudore, E. Bourinet and A. Eschalier (2009). « Animal models of chemotherapy-evoked painful peripheral neuropathies. » Neurotherapeutics 6(4): 620-629.